State Police said the 40-year-old man was driving a 2004 Jeep Wrangler on the northbound side of the highway near Exit 6 when he somehow lost control. The vehicle rolled over several times, police said.
The man's was not released; police said they were still in the process of notifying his family.
The crash happened at about 6 p.m.
The man was transported to Morton Hospital, where he was pronounced dead.
Authorities were investigating what caused the crash.